Jarro-Zymes Plus

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• Similar to Human Pancreatic Enzymes

• Richer in Lipase Than Other Pancreatic Supplements

• Superior to Vegetable Enzymes

• Facilitates the Digestion of Legumes

• Adds to the Sum of Protective Enzymes Available to the Body, Including the Cardio-Protective Elastases

Enzymes released by the pancreas play a significant role in digestion as well as in the overall health of the body. The list of complaints researchers have linked to poor digestion includes acne, allergies, bloating after meals, malabsorption and nutrient deficiencies, various immune dysfunctions, rheumatoid arthritis, dry skin, and the impaired healing of wounds and athletic injuries. Even the control of parasites and yeasts in the digestive tract depends upon secretion of pancreatic enzymes. Jarro-Zymes™ Plus offers the most powerful and convenient approach for supplementing with the full spectrum of pancreatic enzymes.

The Pancreas: A Forgotten Organ

The pancreas produces roughly 1.5 quarts of pancreatic juice each day. This rich mixture of enzymes consists primarily of three families of compounds.

Amylases break down starches and other carbohydrates into simple sugars. The salivary glands secrete amylase into the saliva and carbohydrate digestion continues until glucose (blood sugar) is formed.

Proteases are involved in the digestion of proteins. Proteins are first acted upon in the stomach by hydrochloric acid, pepsin and gastrin. Then the pancreatic components trypsin, chymotrypsin and carboxypeptidase help to complete the reduction of large protein molecules to di- and tripeptides and into free amino acids.

Lipase is the enzyme which the pancreas secretes to aid the digestion of fats. This compound helps to break down dietary fats called triglycerides – 35% of the typical American diet – into monoglycerides and free fatty acids. Fats are the most difficult of foods to properly digest, yet they are necessary sources of important vitamins and other nutrients, such as the vitamins A and E and the heart-protecting omega-3 fatty acids. Jarro-Zymes™ Plus uses the best source of lipase and is superior to other pancreatic preparations in this regard.

Considerable evidence now exists that supplemental pancreatic enzymes can be absorbed into the blood stream and may be reabsorbed from the gut and recirculated. Therefore, supplementation with pancreatin may have sparing effects upon the body’s production of digestive enzymes.

More Than Just a Digestive Aid

Digestive enzymes play many roles in the body. Incomplete digestion can allow large protein molecules, such as those from milk, to pass through the intestinal lining and activate immune responses. This is one source of allergies.

Pancreatic proteolytic or protein-digesting enzymes have benefits in controlling one of the negative consequences of inflammation, a build-up of the substance fibrin. Fibrin is a compound found in the blood vessels which can lead to blood clots and a narrowing of the vessel walls at sites of tissue injury and inflammation. Proteolytic enzymes encourage fibrinolysis, the breakdown of fibrin so that it can be removed from areas of damage.

Proteolytic enzymes also act in the body to help dissolve circulating immune complexes. These complexes are active in a number of autoimmune conditions. In clinical trials, enzyme preparations have proven effective in reducing the level of circulating immune complexes.

Pancreatic Elastases and Arterial Health

The beneficial effects of elastase in experimental atherosclerosis have been reported in numerous studies. In one experiment, a pancreatic extract with elastolytic activity was shown to prevent excessive platelet aggregation (“clumping”) and to reduce the formation of blood clots (thrombosis). Excessive clotting is a factor in several diseases. In addition, elastase was capable of inhibiting the artificially-induced shedding of cells from the endothelium. This is one test for tendencies toward micro-hemorrhages in blood vessel linings.

In these tests, elastase was able to increase the flexibility of red blood cells as well as their resistance to certain types of damage. When animals were fed an atherogenic diet, elastase limited the accumulation of damaged lipoproteins in the aorta wall just as it reduced an artificially enhanced accumulation of calcium. In other words, pancreatic elastase proved to be protective of arterial health.

Why Pancreatin Should Not be Enterically Coated

The food mass which leaves the stomach is called “chyme” and is quite acidic because of the presence of hydrochloric acid. This acidity stimulates the lining of the upper small intestine (the duodenum) to secret two hormones (secretin and cholecstokinin/CCK). These hormones, in turn, cause the ducted portion of the pancreas to release both pancreatin and sodium bicarbonate (to neutralize the acidity). The alkalizing effect of the bicarbonate allows the pancreatin to continue its digestive functions and to fully break down fats.

During the normal course of digestion, pancreatin is mixed completely with the chyme. Human and animal experiments have repeatedly shown that supplemental pancreatin is not only not damaged by stomach acid, but that it is advantageous to have the pancreatin mixed with the food before the food leaves the stomach. Enterically coated tablets of pancreatin don’t allow replication of this normal digestive process.

Taking Jarro-Zymes™ Plus with one or two glasses of unchilled fluid with a meal stimulates the production of gastrin and stomach acid. With the completion of protein digestion, the higher acid content of the stomach will stimulate the proper release of bicarbonate and pancreatin as the chyme enters the small intestine.

Superior to Vegetable Enzymes

The human body produces pancreatic enzymes for digestion. In individuals who need to supplement their production of pancreatin, plant-derived enzymes cannot serve to replace the full range of pancreatin’s enzymatic functions. What’s more, in severe pancreatitis, only pancreatic enzymes are of use.

To provide benefits like those produced by the body’s own enzymes, a supplement must be very similar to those enzymes. Porcine pancreatin is the enzyme source most like that produced in the human body. Ox pancreatin is not an adequate substitute for these enzymes. Jarro-Zymes™ Plus uses only porcine pancreatin, to most closely replicate the body’s own production.

The Seal of Quality

Jarro-Zymes™ Plus includes pancreatic enzymes which are prepared to match USP standards of potency and purity. These standards give ratings in terms of enzyme activity rather than in terms of simple weight. Each 425 mg. capsule provides the following amounts of activity:

Lipase 10,000 USP Units (capable of digesting 10 grams of fats)

Protease 50,000 USP Units (capable of digesting 50 grams of milk protein)

Amylase 50,000 USP Units (capable of digesting 50 grams of dry potato starch)

These components are derived from freeze-dried, defatted and concentrated porcine pancreas. Also included are 625 AGS Units of activity of alpha-galactosidase, an enzyme which improves the ability to digest beans and other legumes. AGS Units are the activity of digesting the starches raffinose and stachyose.

Usage and Safety

Jarro-Zymes™ Plus from Jarrow FORMULAS® is used as a dietary supplement. One to three capsules are taken with each meal along with adequate amounts of fluids. These capsules should be swallowed quickly with a full glass of liquid and must not be chewed.

Reference

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Source: Jarrow Formulas