Glucose Optimizer Brochure- Supports Glucose Metabolism and Antioxidant Status

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• Alpha-Lipoic Acid – a powerful activator of glucose transport

• Gymnema Sylvestre – promotes pancreatic betacell metabolism – plus a blend of herbs used traditionally for their glucose-regulating properties

• Designed to encourage insulin activity and glycogen production and storage

• Provides the vitamins and minerals most important for the metabolism of glucose and the production of cellular energy in the form of ATP

• Enhances antioxidant status and the health of the capillaries and other blood vessels

A Comprehensive and Synergistic Combination of Nutrients and Herbal Extracts to Nutritionally Support Blood Sugar Balance

Dietary Sources of Blood Sugar Imbalances

In 1975, T.L. Cleave, M.D., published The Saccharine Disease, which argues that blood sugar control problems are characteristic of modern Western diets. Twenty years later, Americans ages 2 years and older consumed the equivalent of 82 grams (2.9 ounces) of sugars per day from added sweeteners, which accounted for 16% of all calories consumed. This figure, which comes to more than 65 pounds per person per year(!), does not include the sugars added to foods as binders, fillers, preservatives, and so forth, nor the sugars that occur naturally in fruits, milk, etc. In recent years, in part as a result of the campaign to reduce the amount of fat in the American diet, the consumption of simple sugars has rocketed even further upward, with per capita consumption now reaching between 149 and 152 pounds per year!

Blood Lipids - Blood Sugar - Antioxidant Balance

High levels of blood fats and blood sugar interfere with each other’s proper regulation and metabolism. On the one hand, the presence of excess glucose in the blood interferes with the use of fat for energy and, through the action of the liver, elevates the level of triglycerides and their storage as fat. On the other hand, the presence of excess fats in the blood interferes with the disposal of glucose.

To optimize the regulation of blood sugar, both bloodglucose levels and blood fat levels must be taken into account. This is why Glucose Optimizer® provides a unique combination of ingredients designed to address both of these issues while simultaneously protecting the body against the oxidative stress associated with elevated levels of blood glucose and insulin.

Chromium

Chromium is the mineral most associated with blood sugar control because in its trivalent form it appears to improve the absorption of glucose into the cells. Chromium potentiates the effects of insulin by improving its ability to bind to its cellular receptor. If a lack of chromium is responsible for the suboptimal clearance of blood sugar by insulin, supplemental chromium will mean that less insulin is needed to control blood sugar levels. Energy levels therefore can be stabilized and the extreme fluctuations of hunger associated with hypoglycemia can be avoided because there is no longer an excessive release of insulin. The usefulness to the dieter and to those with tendencies to high blood sugar is obvious. Just as important, however, is the fact that chromium has been shown to help moderately decrease unwanted blood lipid levels, both of LDL cholesterol and of triglycerides, while actually raising the levels of the desirable HDL fraction of the blood.

Glucose Optimizer Advantages

Contemporary research has identified compounds that have much stronger effects directly upon glucose transport than trivalent chromium, such as alpha-lipoic acid. Niacinamide is another nutrient which significantly modulates glucose metabolism, in part by improving both insulin response and insulin release. All four of these nutrients are found in Glucose Optimizer® and are broadened by the inclusion of herbal extracts that improve pancreatic beta-cell functioning.

Alpha Lipoic Acid: The Antioxidant Glucose Regulator

Known primarily as an antioxidant that protects both waterbased and fat-based tissues, alpha-lipoic acid is also a potent regulator of blood sugar. It has a direct effect upon one or more of the cellular glucose transporters, proteins found inside cells which transport glucose across the cell membrane. alpha-Lipoic acid inhibits the inappropriate release of glucose by the liver, such as when the liver releases yet more glucose into the blood even as the pancreas is releasing insulin to help clear the glucose already present. Of all the nutritional glucose modulators available, alphalipoic acid is the most powerful, most versatile, and most extensively tested.

Gymnema Sylvestre The herb

Gymnema sylvestre has been used in Indian/ Ayurvedic medicine for 2000 years to positively modulate carbohydrate metabolism. Animal studies have confirmed that the herb does indeed reduce blood sugar levels. Other studies demonstrate that gymnema extracts increase liver and pancreas functions, which tend to be weakened in those who are overweight or experience blood sugar regulatory problems. Another significant factor to dieters is the fact that gymnema is claimed traditionally to reduce cravings for sweet foods; it does this by mildly affecting the taste receptors. Western-style researchers have determined that Gymnema sylvestre may work by repairing or regenerating the actual insulin-producing cells of the pancreas and thereby increase insulin output.

Glucose Optimizer

Vitamin C Antioxidant; may improve insulin’s actions; partially dependent upon insulin for entry into the cell

Niacinamide Enhances insulin sensitivity and secretion

Vitamin B-1 Eessential for carbohydrate metabolism, energy production and nerve cell function

Vitamin B-5 Supports the utilization of carbohydrates and fats in energy production

Vitamin B-6 Supports nerve health; inhibits the crosslinking of proteins by sugars

Vitamin B-12 Supports nerve health; important for energy production; methyl donor

Biotin Enhances insulin sensitivity and glucokinase activity in the liver

Folic Acid Methyl donor that works with B-6 and B-12 to lower homocysteine levels

Vitamin E Antioxidant; enhances insulin sensitivity

Magnesium May enhance the secretion and actions of insulin; important for the desaturation of fats and for production of energy in the form of ATP

Manganese Important for blood sugar control, energy production and thyroid function; supports the production of the antioxidant superoxide dismutase (SOD)

Selenium Antioxidant; works with vitamin E; supports immune health

Chromium Part of “glucose tolerance factor;” works with insulin at its receptor site on the cell to improve the cellular absorption of glucose (regulate blood sugar metabolism)

Alpha-Lipoic Acid Antioxidant; enhances insulin sensitivity; mimics insulin’s actions; improves glucose transport into the cells; rehabilitates and spares vitamins C and E; rehabilitates CoQ-10; reduces glycation

Gymnema Sylvestra Increases ability of beta-cells to produce insulin; may reduce taste for sugars (75% gymnemic acids)

Bilberry Extract Supports the production of visual purple in the eye; antioxidant that protects the health of the eyes and capillaries (24% anthocyanosides)

Green Tea Extract Supports the health of the capillaries and other blood vessels (45% polyphenols)

Bitter Melon Mimics some of the actions of insulin to reduce blood sugar levels

Fenugreek Fiber Extract Blood sugar lowering properties

Eucalyptus Leaf Extract Supplies antioxidant bioflavonoids

Taurine Acts as a minor insulin mimic; antioxidant; stabilizes cell membranes

Usage

Take 4 tablets of Glucose Optimizer® per day with meals, preferably 2 tablets with breakfast and 2 tablets with lunch or supper. NOTE: If being treated medically for blood sugar imbalances, check with your qualified healthcare provider before using.

References

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2. Gittleman AL. Get the Sugar Out. (New York: Crown Trade
Paperbacks, 1996); Steward HL, et al. Sugar Busters (1995); U.S.
Department of Agriculture figures.
3. Brand JC, Nicholson PL, Thorburn AW, Truswell AS. Food processing
and the glycemic index. Am J Clin Nutr. 1985 Dec;42(6):
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4. Lipetz P. The Good Calorie Diet. (New York: HarperCollins
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5. Felber J-P, Acheson KJ, Tappy L. From Obesity to Diabetes. (New
York: John Wiley & Sons, 1993), Chapter 4, “Insulin Resistance.”
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literature 1997-1998. Curr Opin Clin Nutr Metab Care. 1998
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antioxidant. Free Radic Biol Med. 1995 Aug;19(2):227-50. Review.
9. Jacob S, Henriksen EJ, Tritschler HJ, Augustin HJ, Dietze GJ.
Improvement of insulin-stimulated glucose-disposal in type 2 diabetes
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Source: Jarrow Formulas